In henochschonlein purpura, some of the bodys small blood vessels become inflamed, which can cause bleeding in the skin, abdomen and kidneys. A 53yearold man presented with a 5day history of eruptions on his legs and right arm that were mildly pruritic. Henoch schonlein purpura hsp, also called immunoglobulin a vasculitis. It is not contagious, so cannot be passed on to other people.
However, all four elements of this tetrad are not required for diagnosis. Henochschonlein purpura is a small vessel vasculitis that affects mainly pediatric patients, characterized by the tetrad of palpable purpura, abdominal pain, arthralgia or arthritis. The american college of rheumatology 1990 criteria for the. The patient had experienced multiple hospitalizations in the prior 12 months and had demonstrated chronic kidney disease, with a serum creatinine level in the 2. It is defined as a condition in which nontraumatic hemorrhage with or without edema may occur in the skin, or subcutaneous tissue, or joints, or viscera, or in any combination of them, and in which the blood platelets are normally abundant. An e,ythematous, urticaria4 slightly edematous lesion that is ill defined on helix and antihelix of ear of an individual who has henochschoenlein purpura. Hsp is caused by an abnormal immune system response in which the bodys immune system attacks the. Iga is a form of antibody that we all make, to protect the lining of the airway, throat, and gut. The schoenlein henoch syndrome is described on the basis of 44 personally observed cases. Henochschoenlein purpura is a type of inflammation of small blood vessels known as vasculitis. Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of hsp. Endoscopy revealed diffuse ulcerations in the stomach, duodenum, and right colon.
Although it can occur at any age, hsp is overwhelmingly a disease of childhood. This pedl guideline is intended to support decision making by trained doctors and must be interpreted appropriately in the clinical context. Other symptoms include painful swelling around the joints and abdominal pain. A study on the onset and prognosis of acute vascular purpura the schoenlein henoch syndrome in children. She has torpid evolution, and gastrointestinal and renal complications. Steroid therapy led to complete resolution of the symptoms. Although the term schonlein henoch purpura is more appro priate historically, henoch schoniein purpura. This is basically a selflimited disease, however the. In the skin, the disease causes palpable purpura small, raised areas of bleeding underneath the skin, often with joint pain and abdominal pain. Please use one of the following formats to cite this article in your essay, paper or report. The syndrome of acute purpura and arthritis in children was first described by schonlein in 1837 i.
Henoch schonlein purpura hsp is a blood vessel disease that mostly affects children and young adults. Case 1 pedia henoch schonlein purpura free download as powerpoint presentation. Biopsies revealed a leukocytoclastic vasculitis in the skin and gastrointestinal tract. Henochschonlein purpura symptoms and causes mayo clinic. The disease causes swelling in the veins of the kidneys, intestines, skin, and joints. Hsp happens in people of all ages, but is most often seen in children under 10 years of age. Schoenlein henoch syndrome with acute scrotal condition simulating torsion of the testis. Vasculitis means inflammation of tiny blood vessels.
Henoch schonlein purpura also known as iga vasculitis, is often called hsp for short. Nearly fatal case of schoenlein henoch syndrome following insect bite. Henochschoenlein purpura, is also known as hsp or shp and is named after two 19th century german doctors who first described it. Henoch schonlein purpura hsp, iga vasculitis what is henoch schonlein purpura hsp, iga vasculitis. Iga is a protein in your body that usually protects your body from infections. Its most common feature is a bright, reddishpurple rash that usually appears on the legs.
In most cases, the diagnosis of hsp can be made by clinical findings, although the presentation can be variable. A 65yearold man presented with a 1week history of abdominal pain and was noted to have acute kidney failure, with a serum creatinine level of 3. Children may develop arthritis inflammation of the. Tiny blood vessels in the body become inflamed or swollen. Henochschonlein purpura, who presented to our department with cutaneous manifestations. It predominantly affects the skin, joints, gastrointestinal. Its not usually serious, but can sometimes lead to kidney problems. Usually, the immune system makes antibodies, or proteins, to protect the body from foreign substances such as bacteria or viruses. Hsp is the most common vasculitis in children, with an incidence of about 10 cases per 100 000 a year. With kidney involvement, there may be a loss of small amounts of blood and. Anaphylactoid purpura in children schonlein henoch syndrome. The manifestations of colicky abdominal pain and of nephritis were added by henoch in 1874 2. Henochschoenlein purpura hsp is a condition in which very small blood vessels capillaries become inflamed.
Case 1 pedia henoch schonlein purpura kidney disease. Henochschonlein purpura is an igamediated, autoimmune, hypersensitivity vasculitis of childhood that results in a triad of symptoms, including a purpuric rash occurring on the lower extremities. The classic symptom of hsp is a red to dark purple rash, called purpura, which is often most severe on the legs and buttocks. Glomerulonephritis hspn occurs in 3050 % of hsp patients, mostly in a mild form but a small percentage of patients present with nephrotic syndrome or renal failure. Henochschoenlein purpura, is also known as hsp or shp and is named after two 19th century german doctors who. The microscopic hallmark of hsp is the deposition of iga an.
Symptoms can begin in children, most commonly between the ages of 4 and 7 years, soon after an upper respiratory tract infection or a streptococcalpharyngitis sore throat infection. We describe a case of an adolescent male with henoch schonlein purpura hsp, presenting with cutaneous and gastrointestinal manifestations. It may be the result of the immune system responding inappropriately to certain triggers. This inflammation is called vasculitis and usually affects the small blood vessels in the skin, bowels and kidneys. Diseases of infancy and childhood 1914 14768890461.
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